日志正文
|
||
问题:顾教授:您好!我经常关注您的博客,觉得您非常了不起。去年因为我的男友患脑干胶质瘤,而与您联系过,也与您通过电话,我的男友最终不幸离开了。当时在网上看到你的介绍,对您抱有很大的希望,希望能够得到您给与的治疗,与您联系,您也很爽快的答应了,同时看了很多的医院及权威,都已经放弃,而您的答复给了我们所有人希望,只是由于当时路途的遥远及我男友病情急剧恶化,没能得到您的帮助,非常可惜,遗憾。从网上查询得知脑干胶质瘤目前还无法攻克,但是看到你的医术精湛,给很多病人解除了痛苦,对您还是很钦佩。希望您能在脑干位置上的恶行肿瘤方面的研究取得更大的成就和突破,使脑干上的恶性肿瘤成为可以治愈的,帮助更多的病患。我想了解一些关于脑干胶质瘤方面的知识。请问脑干胶质瘤发病的原因是什么?胶质瘤是恶性肿瘤吗?如果实施手术割除,是否还会再长?一旦查出是脑干胶质瘤或大脑其他部位的胶质瘤,是否意味着时间已经不多了?年轻人患脑干胶质瘤是否由于生命力旺盛,更容易导致病情的恶化?谢谢! 答复: 您好!脑干位于颅后窝内,俯卧于颅底蝶鞍斜坡上,上接间脑,下端在枕骨大孔处延续为脊髓,脑干向下向上分为延髓、脑桥和中脑三部分。脑干为第Ⅲ~第Ⅻ颅神经的起源地,与嗅神经及视神经有传导反射联系,是上行及下行的长束必经之处。脑干的网状结构中有呼吸及循环中枢,其网状激动系统与意识有密切关系。脑干症状复杂多样,其特点是:病变同侧的周围性颅神经麻痹和对侧的中枢性偏瘫及偏身感觉障碍—交叉性麻痹。 脑桥症状(1)颅神经症状:脑桥病变引起的三叉神经症状以病灶侧面部感觉障碍为主,角膜反射减低或丧失,同侧咀嚼肌萎缩且肌力弱,张口下颌偏向患侧,外展神经麻痹,眼球内斜。(2)感觉障碍:感觉障碍程度不一,有的完全缺失,有的轻度减退。股体感觉障碍及面部感觉可以呈交叉状态。肢体感觉症状又表现为分离性感觉障碍。(3)运动麻痹:多于病灶对侧出现偏瘫。脑桥下部病变时,病侧出现面神经麻痹,对侧出现偏瘫,同时病灶侧尚有外展神经麻痹。(4)小脑症状:小脑症状为为脑桥病变重要的症状之一 ,脑桥与小脑关系密切,脑桥病变时病灶侧出现共济失调及其他小脑症状。(5)精神及睡眠障碍:脑桥病变因损伤脑干网状结构可出现精神障碍、智力下降及睡眠障碍,起初淡漠、嗜睡、悲痛易哭、继之则好动,语言讷吃。 治疗由于目前的显微神经外科技术比较发达,能够进行一部分病人的全切手术。 同时采用节拍式化疗和血管抑制治疗。是可以对一部分患者进行根治的。 下面是一些详细的脑干区域的解剖结构和功能: The figure below on the right shows the entire ventral surface of the brain stem. The lines and arrows connecting the ventral view with the three MRI images are to help you understand what is left and right. Do not worry about the bumps, grooves and nerves shown on this ventral view, that will come later. Right now just orient yourself!! Both the dorsal and ventral surfaces of the brain stem are shown below. We already know what is right and left on the ventral view. Now, take the page out of your notebook and fold it along the dotted line (yes, this is medical school!) and you can see that what lies beneath (is dorsal) the right side of the ventral aspect of the brain stem is the right side of the dorsal aspect of the brain stem, and what lies below the left side of the ventral aspect of the brain stem is left side of the dorsal aspect of the brain stem. Like in the spinal cord, in an axial MRI section of the brain stem ventral is up and dorsal is down. Again we will follow tradition (all neuro textbooks!) and “flip” the section so ventral is down and dorsal up. However, make sure to keep the right/left designation of the axial section MRI. That is, the right side of the patients brain is on your left.
As mentioned earlier, the brain stem includes the (1) medulla, the (2) pons and the (3) midbrain. The brain stem contains 10 cranial nerves, and most of the motor and sensory systems pass through this important region. It is a relatively small region (approximately 7 cm long) that links the forebrain (i.e., cerebral cortex) and the spinal cord and all messages going between the two areas must go through the brain stem. Details regarding the organization of the brain stem will be presented by discussing the nuclear groups and fiber tracts that are present at 10 different caudal to rostral levels. In each of the ten levels, the tracts (fibers) are drawn in black. Therefore, the nuclei (cell bodies) are the clear spaces. The drawing below shows a rough approximation of the location of where the 10 levels are cut on a ventral view of the brain stem. The following ten pages show drawings of these levels and above each level is the appropriate MRI image.
最后修改于 2007-07-19 10:42
阅读(?)评论(0)
|
||
评论 想第一时间抢沙发么?